Welcome to OncoGeneX

Taking Cancer to Trial

"OncoGenex Pharmaceuticals Inc.’s new products could help mitigate the difficulty of treating tumours that rapidly adapt."

Data Provide Ongoing Evidence of Hsp27 as a Potential Therapeutic Target in Advanced Prostate Cancer  

Read More

Phase 1 Study of OGX-427 Shows Early Evidence of Activity in Bladder Cancer

Read More

News & Events

Thursday, May 3 2012

OncoGenex Pharmaceuticals, Inc. Reports Financial Results and Reviews Clinical Development Highlights for First Quarter of 2012

Wednesday, Apr 25 2012

OncoGenex to Webcast Discussion of First Quarter 2012 Financial Results on Thursday, May 3, 2012

Tuesday, Mar 27 2012

OncoGenex Pharmaceuticals to Present at Two Upcoming Investor Conferences

OncoGenex is a biopharmaceutical company uniquely focused on cancer treatment resistance. We are committed to the development and commercialization of first-in-class, innovative therapies that target mechanisms of resistance and that have the potential to re-define treatment paradigms in a variety of cancers.

Product Pipeline

Phase Three

Custirsen is designed to block production of clusterin, a cell survival protein that is over-produced in several cancer types of cancer and in response to many cancer treatments, including hormone ablation therapy, chemotherapy and radiation therapy.

Phase Two

OGX-427 is a second generation antisense drug which, in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27), a cell survival protein found at elevated levels in many human cancers. The development program for OGX-427 aims to demonstrate inhibition of Hsp27 can lead to improved prognosis and treatment outcomes for cancer patients.